Context：Oral contraceptives (OC) are common used in PCOS patients. However, the effects of OCs on sexual function in PCOS patients are unknown. Objective: The aim of this study was to investigate the effects of oral contraceptives on sexual function in PCOS patients. Methods: The online questionnaire was completed by PCOS patients in clinic. Patients: PCOS patients in the Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University. Intervention: Taking oral contraceptives (OC group) or not (NOC group). Main Outcome Measures: The primary endpoint was the Female Sexual Function Index (FSFI) score, with additional questions on contraception, sexual activity, relationship stability, pregnancy and other factors which may influence sexual function. Results: 210 PCOS patients were recruited in this study to participate in the survey using the online questionnaire. Of all women participating, 126 were taking oral contraceptives (OC group) and 84 were not (NOC group). Among OC users, the median FSFI total score was 26.35, and 50.79% showed high risk of FSD. Regarding NOC group, the median FSFI total score was 26.85, 47.62% showed high risk of FSD. There’s no significant difference between two groups (P = 0.635). Also, no differences of FSFI scores were shown in patients taking 35μgEE/2mgCPA, 30μgEE/3mgDRSP, and 30μgEE/150μg Desogestrel. Relationship stability and sexual activity were found to be associated with sexual function in PCOS patients. Conclusions: There’s no difference between oral contraceptive users and nonhormonal contraceptive users in PCOS patients. Different progestins in OCs and the EE dosage in OCs have no significant influence on sexual function in PCOS patients. Regarding PCOS patients, sexual activity and relationship stability may be risk factors of FSD.