Poster Session

P104. Non-Contraceptive Benefits of Contraceptives – Retrospective Study in Clinical Hospital of Obstetrics and Gynecology “Prof Dr Panait Sarbu” Bucharest

Alina Busan (RO), Ioan Boleac (RO), Elena Nada (RO), Marjan Onabi (RO), Cristina Neagu (RO), Manuela Neagu (RO)

[Busan] Clinical Hospital of Obstetrics an Gynecology , [Boleac] Clinical Hospital of Obstetrics an Gynecology , [Nada] Clinical Hospital of Obstetrics an Gynecology , [Onabi] Clinical Hospital of Obstetrics an Gynecology , [Neagu] Clinical Hospital of Obstetrics an Gynecology , [Neagu] Clinical Hospital of Obstetrics an Gynecology

Context: In gynecological practice there are situations in which, for a certain symptomatology, one can resort to hormonal treatment as an alternative to other pharmacological producs or even to surgical treatment. Objective: To determin the usefulness of contraceptives in gynecological pathologies Methodes: We conducted a retrospective study in order to analyze the various situations where the administration of hormonal contraception had therapeutical effect. Patients: We included 180 women treated in our clinic between 01.01.2015-30.09.2017 and we grouped them according to the dominant complain. Thus we obtained 3 groups: A – pelvic pain - 57 patients, B - irregular menstrual cycles - 88 patients, C – changes in menstrual cycle pattern - 45 patients. Interventions: no intervention. We analysed what pathology caused the symptomatology and the opportunity of hormonal treatment. Main Outcome Measures: With regard to group A, after exclusion of pelvic inflammatory disease, patients with dysmenorrhea and dyspareunia, symptomatology frequently associated with endometriosis, adenomyosis or POCS received monophasic oral contraceptives. At 6-month control, the anti-algic administration rate was halved on average, and the patients had a 90% satisfaction rate and continued receiving oral contraceptives. Group B - menstrual disorders, included 88 patients with POCS. They received oral contraceptive therapy with progestin with antiandrogenic action. At the 6-month control, all patients reported regular menstrual cycles, and about half observed decreased acnee and hirsutism. Group C - women in perimenopause 40 -43 years, 15 patients were diagnosed also with uterine leiomyoma for which the opportunity for surgery was considered and it was decided to postpone it. All patients benefited from a levonorgestrel IUD. Of these, only 3 patients have requested IUD removal and surgery within the first 6 months. Of the remaining, 80% observed the improvement of symptoms after the first months. Results: out of 180 patients, 177 had good outcome using contraceptives as an alternative. Conclusions: Although appearing on the market for contraceptive effects, many contraceptive methods can also be used for therapeutic purposes, thus reducing the use of anti-algic, dermatological drugs and even the rate of surgery. It remains to be studied the long-term effect on the endometrial hyperplasia rate in patients with micropolicystic ovaries treated oral contraceptives.