P294. Weight gain and metabolic changes during the menopausal transition in Ecuadorian women.

Denny Salazar-Pousada (EC), Ingrid Morales-Luna (EC), Faustino Perez-Lopez (ES), Peter Chedraui (EC)

[Salazar-Pousada] Institute of Biomedicine, Research Area for Women’s Health, Facultad de Ciencias Médicas, , [Morales-Luna] Institute of Biomedicine, Research Area for Women’s Health, Facultad de Ciencias Médicas, , [Perez-Lopez] Department of Obstetrics and Gynecology, Facultad de Medicina, Universidad de Zaragoza, Hospital Clínico Dr. Lozano Blesa, Zaragoza, Spain., [Chedraui] Universidad Católica de Santiago de Guayaquil

Background: During the menopausal transition metabolic and hormonal changes occur. As women age weight increases affecting their quality of life. Objective: To determine weight gain and metabolic changes in mid-aged women. Method: This was a cross-sectional study in which 202 Ecuadorian women aged 40 to 69 to whom weight (kg), height (m), body mass index (BMI, kg/m2), waist circumference (cm) and glucose levels were determined. Results: Median age of the cohort was 50 years, with 56.4% being postmenopausal; overall 50% presented abdominal obesity of which 66.3% were postmenopausal, 36.7% sedentary and 18.8% had high fasting glucose (≥ 100 mg/dl). Obesity determined by BMI was higher in postmenopausal women (36.8%) as compared to pre- and perimenopausal ones (15.4% and 33.3%, respectively). There was a non-significant trend for postmenopausal women to present higher mean glucose levels as compared to pre- and perimenopausal. Conclusion: In this mid-aged female sample weight and fasting glucose levels increased during the menopausal transition.